Product Description
1. Technical Specifications:
|
Medicine Type
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Allopathic
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|
Usage
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Commercial, Clinical, Hospital, Personal
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Packaging Size
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120 Tablet
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Packaging Type
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Bottle
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2. Product Description
Sorafenat 200mg Tablet contains Sorafenib, a multikinase inhibitor used to treat advanced cancersincluding hepatocellular carcinoma (liver cancer), advanced renal cell carcinoma (kidney cancer), and differentiated thyroid carcinoma (papillary/follicular/Hurthle-cell types) .
It works by blocking tumor cell proliferation and angiogenesis by inhibiting multiple receptor tyrosine kinases such as VEGFR and PDGFR .
3. Product Highlights
| Attribute |
Details |
| Brand |
Sorafenat 200mg Tablet (Sorafenib) |
| Manufactured By |
Natco Pharma Ltd, India |
| Generic Name |
Sorafenib |
| Strength |
200mg |
| Dosage Form |
Filmcoated oral tablet |
| Packaging Type |
Blister strip in carton packaging |
| Therapeutic Category |
Tyrosine kinase inhibitor / Oncology agent |
| Application Area |
Treatment of advanced liver, kidney, and thyroid cancer |
| Formulation |
Solid filmcoated tablet |
| Storage Conditions |
Store below 30C in a dry place; keep out of reach of children |
| Shelf Life |
As per batch expiry (usually 2436 months per packaging) |
| Regulatory Compliance |
Manufactured in GMPcertified facility by Natco Pharma |
4. Therapeutic Uses
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Hepatocellular carcinoma (liver cancer) unresectable or advanced stage
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Advanced renal cell carcinoma (kidney cancer)
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Differentiated thyroid carcinoma papillary, follicular, and Hurthle-cell types after radioactive iodine failure
5. Safety Profile & Side Effects
Common side effects:
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Loss of appetite, weight loss, nausea, vomiting
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Hair thinning/loss, skin rash, hand-foot skin reactions
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Hypertension, fatigue, headache, diarrhea, stomach discomfort
Less common or serious risks:
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Severe bleeding, gastrointestinal perforation
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Cardiac events (QTc prolongation, heart failure), tumor lysis syndrome
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Hematological toxicity: reduced platelet or WBC counts
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Hypoglycemia in diabetic patients, delayed wound healing, thyroid dysfunction
6. Precautions
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Take on empty stomach at least 1 hour before or 2 hours after high-fat meals to ensure efficacy
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Regular blood pressure monitoring, especially during the first 6 weeks of treatment
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Monitor blood counts, liver and kidney function, and thyroid function periodically
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Avoid in patients with severe liver or kidney impairment unless dose is adjusted
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Contraindicated in pregnancy and breastfeeding; effective contraception recommended during and up to 6 months after treatment
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Avoid use in children or adolescents (<18years) safety not established
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Avoid alcohol; may increase side effect risk such as nausea or dizziness
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Inform doctor about other medications such as warfarin, antibiotics, antiepileptics, PPIs, cardiac agents due to potential interactions
7. Interactions
Drug interactions may affect its efficacy and increase adverse effects. Consult your healthcare provider if taking:
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Anticoagulants: warfarin, phenprocoumon, dabigatran
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Antibiotics: rifampicin, neomycin
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Antiepileptics: carbamazepine, phenytoin, phenobarbital
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Others: dexamethasone, digoxin, midazolam, doxorubicin, paclitaxel, cisplatin, gemcitabine, PPIs, St Johns wort
Powerful Cancer ManagementSorafenat 200mg Tablet is specially formulated with Sorafenib to help manage advanced cancers, notably liver, kidney, and thyroid cancers. Its targeted approach aims to slow cancer cell growth, offering a valuable option in oncology treatment. Sorafenat is widely trusted by healthcare providers throughout India, thanks to its efficacy and reliable sourcing.
Safe Storage and HandlingTo maintain the potency of Sorafenat 200mg Tablet, it is essential to store the product in a cool and dry place, away from direct sunlight. Proper storage ensures the tablets effectiveness throughout its one-year shelf life. Always check the expiry date before use to guarantee maximum benefit from the medication.
FAQs of Sorafenat 200mg Tablet:
Q: How should Sorafenat 200mg Tablet be taken?
A: Take Sorafenat 200mg Tablet exactly as prescribed by your doctor, usually once or twice daily on an empty stomach. Do not crush or break the tablet, and swallow it whole with water. Follow your healthcare providers directions for the best results.
Q: What conditions is Sorafenat 200mg Tablet used to treat?
A: Sorafenat 200mg Tablet is primarily indicated for the treatment of advanced cancers, such as liver cancer (hepatocellular carcinoma), kidney cancer (renal cell carcinoma), and thyroid cancer. Your doctor will determine its suitability based on your diagnosis.
Q: When should I start to see the benefits of Sorafenat 200mg Tablet?
A: The time to see noticeable benefits varies for each individual and depends on the type and stage of cancer being treated. Regular follow-up visits and monitoring by your healthcare provider will help assess its effectiveness.
Q: Where should Sorafenat 200mg Tablet be stored?
A: This medication should be kept in a cool and dry place, away from direct heat and moisture. Always store the tablets in their original packaging and out of reach of children.
Q: What is the process for obtaining Sorafenat 200mg Tablet in India?
A: You can obtain Sorafenat 200mg Tablet through authorized distributors, exporters, suppliers, traders, and wholesalers within India. A valid prescription from a licensed medical practitioner is required for purchase.
Q: How does Sorafenat 200mg Tablet benefit cancer patients?
A: Sorafenat 200mg Tablet works by inhibiting the growth of cancer cells and blocking certain enzymes involved in tumor progression. This mechanism helps to slow disease advancement and may improve patient outcomes.
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