Posid 100mg Injection

Product Description

1. Technical Specifications

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2. Product Description

Posid (Etoposide) Injection is a cytotoxic anticancer drug.
It belongs to the epipodophyllotoxin derivatives and acts as a topoisomerase II inhibitor, preventing DNA unwinding and repair. This results in DNA strand breaks and apoptosis of rapidly dividing cancer cells.

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3. Product Highlights

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4. Therapeutic Uses

• Small cell lung cancer (SCLC)

• Testicular cancer (in combination regimens)

• Hodgkins lymphoma and Non-Hodgkins lymphoma

• Acute myeloid leukemia (AML) and other leukemias

• Part of several combination chemotherapy protocols (e.g., BEP, EP, CHOP-like regimens)

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5. Side Effects

Common:

• Nausea, vomiting, loss of appetite

• Hair loss (alopecia)

• Fatigue, weakness

• Low blood counts (neutropenia, anemia, thrombocytopenia)

• Mouth ulcers (stomatitis)

Serious / Severe:

• Severe myelosuppression (risk of infection, bleeding, anemia)

• Hypotension (if infused too rapidly)

• Secondary leukemia (rare, long-term risk)

• Allergic reactions (flushing, rash, bronchospasm, anaphylaxis)

• Hepatic and renal toxicity (with high doses or impaired function)

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6. Precautions

• Blood Monitoring: CBC before and during treatment (risk of bone marrow suppression).

• Infusion Rate: Administer slowly (3060 min) to avoid hypotension.

• Liver & Kidney Function: Monitor closely; dose adjustment may be needed in impairment.

• Pregnancy & Breastfeeding: Contraindicated teratogenic and harmful to fetus.

• Drug Interactions:

  • Avoid concurrent use with other strong myelosuppressive drugs (additive toxicity).

  • Cyclosporine increases etoposide exposure.

• Handling Precautions: Cytotoxic must be handled by trained personnel with protective equipment.

Clinically Proven Adult Medication

Posid 100mg Injection is specifically formulated for adult patients under strict medical supervision. It is designed to ensure effective treatment for its recommended medical indications. With precise dosage guidelines and careful administration, this injectable is trusted by healthcare providers across hospitals and clinics. Healthcare professionals should always refer to medical instructions for optimal results and safety.


Proper Handling and Storage Instructions

To ensure the effectiveness of Posid 100mg Injection, always store it in a cool, dry place away from direct sunlight. This not only maintains the drugs stability, but also preserves its therapeutic properties. Medical staff and distributors are encouraged to adhere to these instructions for reliable administration and extended shelf life.