Bendit Bendamustine Hydrochloride Injection

Product Description

1. Technical Specifications

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2. Product Description

Bendit 100mg Injection contains Bendamustine Hydrochloride, an alkylating agent with a unique structure that combines properties of both alkylating agents and purine analogs.

It causes DNA cross-linking, leading to inhibition of DNA replication and transcription, and ultimately cancer cell death.

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3. Product Highlights

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4. Therapeutic Uses

• Chronic Lymphocytic Leukemia (CLL) (first-line therapy in selected patients)

• Indolent Non-Hodgkins Lymphoma (NHL) (when disease progresses during or within 6 months of rituximab treatment)

• Multiple Myeloma (in combination with prednisone, for patients unsuitable for standard therapy)

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5. Side Effects

Common:

• Nausea, vomiting, diarrhea

• Fatigue, weakness

• Loss of appetite

• Rash, fever

• Myelosuppression (neutropenia, anemia, thrombocytopenia)

Serious / Severe:

• Severe infections due to immunosuppression

• Hepatotoxicity (liver enzyme elevation, hepatitis reactivation)

• Tumor lysis syndrome (rare but serious)

• Infusion-related reactions (fever, chills, rash)

• Secondary malignancies (long-term risk)

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6. Precautions

• Blood Monitoring: Regular CBC to monitor for neutropenia, anemia, thrombocytopenia.

• Liver & Kidney Function: Monitor LFTs and renal parameters; dose adjustment may be required.

• Infection Risk: Avoid live vaccines; take prophylactic antibiotics if advised.

• Pregnancy & Breastfeeding: Contraindicated (teratogenic). Effective contraception required.

• Drug Interactions: Use caution with CYP1A2 inhibitors/inducers. Avoid concurrent use with other strong myelosuppressive drugs unless prescribed.

• Hypersensitivity: Pre-medication may be advised to reduce infusion reactions

Precision Formulation for Clinical Use

Bendit Bendamustine Hydrochloride Injection offers reliable therapeutic support for adults, formulated as a stable liquid injection. Adhering to strict manufacturing standards in India ensures consistent quality and safety for clinical application. Each batch undergoes thorough quality checks before distribution.


Effective Distribution and Supply Chain

This injection is widely available across India through an established network of distributors, exporters, suppliers, traders, and wholesalers. Efficient logistics ensure that healthcare providers can access this essential medication seamlessly and promptly for patient care needs.