Paclitaxel 100mg injection

Product Description

1. Technical Specifications

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2. Product Description

Intaxel 100mg Injection contains Paclitaxel, a cytotoxic anticancer drug belonging to the Taxane class.
It works by stabilizing microtubules and preventing their disassembly, which disrupts normal cell division (mitosis), leading to cell death.

It is used as a first-line and subsequent therapy in several cancers, often in combination with other chemotherapy drugs.

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3. Product Highlights

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4. Therapeutic Uses

• Ovarian Cancer: First-line and relapsed cases (often with cisplatin).

• Breast Cancer: Adjuvant and metastatic settings, including HER2+ (with trastuzumab).

• Non-Small Cell Lung Cancer (NSCLC): In combination with platinum-based drugs.

• Kaposis Sarcoma (AIDS-related): For patients unresponsive to other treatments.

• Also used in head & neck cancers, bladder cancer, prostate cancer, cervical cancer (as per oncologist guidance).

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5. Side Effects

Common:

• Nausea, vomiting, diarrhea

• Alopecia (hair loss)

• Fatigue, weakness

• Myalgia (muscle pain), arthralgia (joint pain)

• Mouth sores

Serious / Severe:

• Bone marrow suppression: neutropenia, thrombocytopenia, anemia

• Hypersensitivity reactions: flushing, rash, low blood pressure, breathing difficulty (requires premedication with corticosteroids + antihistamines)

• Peripheral neuropathy: numbness, tingling in hands/feet

• Cardiac issues: arrhythmias, bradycardia, hypotension

• Severe infections due to low immunity

• Hepatotoxicity in patients with liver dysfunction

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6. Precautions

• Premedication: Mandatory with steroids + antihistamines to prevent hypersensitivity reactions.

• Bone Marrow Monitoring: CBC must be done before each cycle; dose adjustments needed if neutropenia occurs.

• Liver Impairment: Use with caution; dose modification required.

• Pregnancy & Breastfeeding: Contraindicated; paclitaxel is teratogenic.

• Drug Interactions:

  • Avoid concomitant use with CYP3A4 inhibitors/inducers (ketoconazole, erythromycin, rifampicin).

  • Administer paclitaxel before cisplatin (if used in combination) to reduce toxicity.

• Neuropathy: Patients should report numbness, tingling, or weakness.

Highly Effective Oncology Treatment

Paclitaxel 100mg Injection is a proven antineoplastic agent commonly prescribed for various cancers. Administered as an intravenous liquid, this medication supports healthcare professionals in delivering timely and targeted oncological care. Its efficacy lies in interrupting cancer cell growth, giving patients optimized treatment outcomes under doctor supervision.


Safe Handling and Storage Practices

Proper storage is crucial for maintaining Paclitaxel 100mg Injections potency. It should be kept in a cool, dry place as recommended. This ensures the medicine remains stable, effective, and ready for export, distribution, or administration across medical facilities in India. Following storage guidelines helps preserve its quality from supplier to end-user.