Tykerb 250 Mg Tablet

Product Description

1. Technical Specifications

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2. Product Description

Tykerb 250 mg Tablet contains Lapatinib, a tyrosine kinase inhibitor (TKI). It specifically targets HER2 (ErbB2) and EGFR (ErbB1) receptors, blocking tumor cell proliferation and survival signals. It is mainly used in the treatment of HER2-positive breast cancer, often in combination with capecitabine or letrozole.

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3. Product Highlights

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4. Therapeutic Uses

• Advanced or Metastatic HER2-Positive Breast Cancer

  • In combination with capecitabine after prior therapy including trastuzumab and taxane

  • In combination with letrozole for postmenopausal women with hormone receptor-positive, HER2-positive metastatic breast cancer

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5. Side Effects

Common:

• Diarrhea, nausea, vomiting

• Fatigue, weakness

• Rash, dryness, itching

• Loss of appetite

• Mouth sores

Serious / Severe:

• Cardiac toxicity: Decreased left ventricular ejection fraction (LVEF), heart failure

• Hepatotoxicity: Elevated liver enzymes, liver injury

• Severe diarrhea leading to dehydration

• Pulmonary toxicity (rare but serious)

• QT prolongation (heart rhythm changes)

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6. Precautions

• Cardiac Monitoring: LVEF must be checked before and during therapy.

• Liver Function: Regular monitoring of liver enzymes is required.

• Pregnancy & Breastfeeding: Contraindicated; can cause fetal harm.

• Drug Interactions:

  • CYP3A4 inhibitors (ketoconazole, clarithromycin) toxicity

  • CYP3A4 inducers (rifampicin, phenytoin, carbamazepine) effectiveness

  • QT-prolonging drugs (amiodarone, quinidine) risk of arrhythmia

• Diarrhea Management: Prompt treatment with anti-diarrheal agents recommended.

High-Quality Oncology Medication

Tykerb 250 Mg Tablet stands out as a reliable option for patients seeking advanced cancer treatments. Originating from India, it meets stringent pharmaceutical standards. Packaged efficiently to maintain potency, each tablet delivers precision and efficacy tailored to medical needs. Distributors and wholesalers ensure a steady supply for hospitals and clinics both domestically and internationally.


Proper Storage and Handling

To preserve its quality, Tykerb 250 Mg Tablet must be stored in a cool and dry environment. Exposure to heat or moisture may compromise the efficacy of the product. Its one-year shelf life assures long-term utility when stored as recommended, making it convenient for stockists managing inventory and supply chains.