Tigebax Injection

Product Description

1. Technical Specifications

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2. Product Description

Tigebax Injection contains Tigecycline, a broad-spectrum glycylcycline antibiotic structurally related to tetracyclines. It is used to treat complicated infections caused by multidrug-resistant organisms. Tigecycline works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, thereby preventing bacterial growth.

It is generally reserved for complicated infections where other antibiotics may not be effective.

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3. Product Highlights

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4. Therapeutic Uses

• Complicated intra-abdominal infections (cIAI)

• Complicated skin and soft tissue infections (cSSTI)

• Community-acquired bacterial pneumonia (CAP)

• Sometimes used off-label in multidrug-resistant (MDR) bacterial infections, including MRSA and Acinetobacter infections

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5. Side Effects

Common:

• Nausea, vomiting, diarrhea

• Abdominal pain

• Headache, dizziness

• Increased liver enzymes

Serious / Severe:

• Hypersensitivity reactions

• Pancreatitis (rare but severe)

• Coagulopathy (bleeding disorders)

• Hepatic dysfunction

• Increased risk of mortality in certain serious infections (as per clinical warnings)

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6. Precautions

• Pregnancy & Breastfeeding: Not recommended; may cause harm to fetus.

• Liver Function: Dose adjustment may be required in hepatic impairment.

• Superinfection Risk: Long-term use may cause overgrowth of non-susceptible organisms (fungal infections).

• Allergy: Contraindicated in patients with hypersensitivity to tigecycline or tetracycline-class antibiotics.

• Children: Safety not established below 18 years.

• Drug Interactions: Use cautiously with anticoagulants (warfarin), cyclosporine, tacrolimus monitor closely.

• Mortality Risk: FDA has issued warnings about a slightly higher mortality risk in patients treated with tigecycline compared to other antibiotics; should be used only when alternatives are not suitable.

Precision Formulation for Targeted Therapy

Tigebax Injection offers an effective solution for treating severe infections, emphasizing reliability and secure delivery through intravenous administration. Engineered for adults and prescribed by qualified doctors only, this medication prioritizes patient safety and therapeutic efficacy. The product is distributed across India, maintaining quality throughout every step of the supply chain.


Production and Distribution in India

Manufactured in India, Tigebax Injection upholds stringent quality standards and is available to healthcare providers via a network of authorized distributors, suppliers, exporters, and wholesalers. Each batch is subject to rigorous controls, ensuring that medical professionals receive a trusted and effective medication when treating adult patients.