Tafnat 25 Mg Tablet

Product Description

1. Technical Specifications

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2. Product Description

Tafnat 25 mg Tablet contains Tenofovir Alafenamide (TAF), a nucleotide reverse transcriptase inhibitor (NRTI).
It is primarily used in the treatment of chronic Hepatitis B virus (HBV) infection and in combination with other antiretroviral medicines for HIV-1 infection.

Compared to Tenofovir Disoproxil Fumarate (TDF), TAF is a newer prodrug with higher efficacy at lower doses and reduced risk of kidney and bone side effects.

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3. Product Highlights

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4. Therapeutic Uses

• HIV-1 Infection: Used in combination with other ARVs as part of HAART regimen

• Chronic Hepatitis B Infection: Reduces viral load, prevents liver damage and cirrhosis

• Prevention of HIV Transmission (PrEP): Sometimes used in combination regimens

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5. Side Effects

Common:

• Headache, nausea, abdominal pain

• Fatigue

• Diarrhea

Serious (rare):

• Lactic acidosis (very rare)

• Severe liver problems (hepatomegaly, steatosis)

• Kidney dysfunction (less frequent than TDF)

• Bone mineral density loss (less compared to TDF)

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6. Precautions

• Use under specialist supervision for HIV/HBV treatment

• Monitor liver function and kidney function regularly

• Caution in patients with pre-existing liver or kidney disease

• Avoid sudden discontinuation in HBV patients (can cause severe flare-up of hepatitis)

• Not recommended in pregnancy unless prescribed by physician

• Avoid concomitant use with strong P-gp inducers (e.g., rifampin, carbamazepine, phenytoin) as they reduce drug levels

Storage and Handling

Proper storage ensures Tafnat 25 Mg Tablet maintains its quality and potency. Keep the tablets in a cool, dry place, away from direct sunlight and moisture. Make sure the container is tightly closed and stored out of the reach of children. Avoid storing the medicine in the bathroom or near sources of heat to prevent degradation.


Target Users and Dosage

Tafnat 25 Mg Tablet is suitable only for adults and should never be used without a doctors recommendation. The dosage regimen is determined by a healthcare professional based on individual needs and medical conditions. Adhering strictly to the prescribed dosage is crucial for achieving the intended health benefits and preventing adverse effects.