Scemblix 40mg tablet

About Scemblix 40mg tablet

1. Technical Specifications

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2. Product Description

Scemblix (Asciminib) is a first-in-class allosteric BCR-ABL1 inhibitor used in the treatment of chronic myeloid leukemia (CML) in patients resistant or intolerant to prior tyrosine kinase inhibitors. It binds to the myristoyl pocket of BCR-ABL1, distinct from the ATP-binding site, inhibiting leukemic cell proliferation.

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3. Product Highlights

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4. Therapeutic Uses

• Chronic Myeloid Leukemia (CML):

  • Adult patients with Ph+ CML in chronic phase resistant or intolerant to two or more TKIs

  • Alternative therapy in patients with specific BCR-ABL1 mutations resistant to other TKIs

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5. Side Effects

Common:

• Fatigue, headache

• Nausea, diarrhea, constipation

• Musculoskeletal pain (joint or muscle pain)

• Rash, edema

Serious / Severe:

• Myelosuppression: neutropenia, thrombocytopenia, anemia

• QT interval prolongation (cardiac monitoring recommended in high-risk patients)

• Hepatotoxicity: elevated liver enzymes

• Pancreatitis (rare)

• Severe infections due to cytopenia

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6. Precautions

• CBC and liver function tests: Monitor regularly

• Cardiac monitoring: For patients at risk of QT prolongation

• Pregnancy & Breastfeeding: Contraindicated; use effective contraception

• Drug Interactions: Avoid strong CYP3A inhibitors or inducers; monitor closely if co-administered

• Administration Advice: Swallow whole; do not crush or chew; maintain consistent daily timing

100% Yeast-Based Enzyme Preparation

Scemblix 40mg tablet is formulated using only pure yeast, ensuring a consistent and natural source of enzymes. This makes it suitable for consumers seeking enzyme supplements free from animal derivatives or synthetic additives. Manufactured in India, this product is distributed nationwide through trusted suppliers.


Easy-to-Use Oral Tablet

Packed in tablet form, Scemblix is convenient for daily use. Each tablet contains a standard 40mg dose, making it simple to incorporate into your routine. The tablet format supports accurate dosage and ease of transport, supporting on-the-go lifestyles.


Storage and Shelf Life

For best results, Scemblix should be stored in a cool and dry place. Strict adherence to these storage conditions is necessary to preserve the products quality during its shelf life of one month. Proper storage helps maintain the effectiveness of the enzyme preparation.