Zuvirab Vaccine

Zuvirab Vaccine

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उत्पाद विवरण

1. Technical Specifications

Attribute Details
Brand Name Zuvirab
Generic Name Rabies Human Monoclonal Antibody / Rabies Vaccine (depending on formulation)
Strength 0.5 ml per vial (single dose)
Dosage Form Injection (suspension for intramuscular use)
Packaging Size Single vial (0.5 ml)
Manufacturer Zydus Cadila Healthcare Ltd.
Therapeutic Class Immunobiological / Vaccine
Medicine Type Allopathic

2. Product Description

Zuvirab 0.5 ml Injection is a purified inactivated rabies vaccine used for both pre-exposure prophylaxis and post-exposure prophylaxis of rabies infection.
It stimulates the bodys immune system to produce antibodies against the rabies virus, thereby preventing the disease after suspected exposure (e.g., dog bites, scratches, or contact with potentially rabid animals).


3. Product Highlights

Attribute Details
Indication Prevention of rabies infection
Application Area Pre-exposure immunization, Post-exposure treatment
Administration Intramuscular injection (deltoid region in adults, anterolateral thigh in children)
Schedule As per WHO & National Guidelines usually multiple doses required for full protection
Storage Conditions Store at 28 C (Refrigerated). Do not freeze.

4. Therapeutic Uses

  • Pre-exposure prophylaxis: For individuals at high risk (veterinarians, animal handlers, lab workers, travelers to endemic areas).

  • Post-exposure prophylaxis: After suspected rabies exposure (animal bites, scratches, or contact with saliva).

  • Administered along with Rabies Immunoglobulin (RIG) in category III exposures (severe bites).


5. Side Effects

Common:

  • Pain, redness, or swelling at injection site

  • Mild fever

  • Headache, dizziness

  • Fatigue, malaise

Rare but serious:

  • Severe allergic reaction (anaphylaxis)

  • Neurological reactions (extremely rare)


6. Precautions

  • Should only be given under medical supervision.

  • Must not be injected into the gluteal region (reduced effectiveness).

  • Contraindicated in individuals with severe allergic reaction to previous rabies vaccination or any vaccine component.

  • Pregnancy and breastfeeding: can be used when risk of rabies exposure is high (benefit outweighs risk).

  • Immunocompromised patients may require additional doses or monitoring for antibody response.

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