Dacotin 100 Infusion

Product Description

1. Technical Specifications

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2. Product Description

Dacotin 100 Infusion contains Oxaliplatin, a platinum-based chemotherapy medicine. It works by binding to DNA and forming cross-links, which prevents DNA replication and transcription, leading to cancer cell death.

It is most commonly used in combination with 5-Fluorouracil (5-FU) and Leucovorin as part of the FOLFOX regimen for colorectal cancers. Administration is strictly under the supervision of an oncologist.

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3. Product Highlights

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4. Therapeutic Uses

• Adjuvant treatment of stage III colorectal cancer after complete resection of the primary tumor

• First-line treatment of advanced/metastatic colorectal cancer (in combination with 5-FU & Leucovorin)

• Sometimes used in other solid tumors as per oncologists discretion

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5. Side Effects

Common:

• Nausea, vomiting, diarrhea, abdominal pain

• Fatigue, weakness

• Loss of appetite

• Anemia, thrombocytopenia, neutropenia

• Peripheral neuropathy (cold-induced tingling, numbness, burning sensation)

Serious / Severe:

• Severe allergic reactions (rash, breathing difficulty, anaphylaxis)

• Nephrotoxicity (rare, less severe than cisplatin)

• Hepatotoxicity

• Laryngopharyngeal dysesthesia (tightness in throat, difficulty breathing, often triggered by cold)

• Severe infections due to immunosuppression

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6. Precautions

• Neuropathy: Monitor closely; dose reduction or discontinuation if severe.

• Kidney Function: Use caution in renal impairment; dose adjustment may be needed.

• Blood Counts: CBC monitoring required before each cycle; avoid if severe neutropenia or thrombocytopenia.

• Pregnancy & Breastfeeding: Contraindicated; effective contraception recommended during and several months post-treatment.

• Drug Interactions: Use caution with nephrotoxic agents (aminoglycosides, amphotericin B) and other myelosuppressive chemotherapy.

• Cold Sensitivity: Patients should avoid exposure to cold (drinks, weather, objects) during and shortly after infusion due to risk of neuropathy.

Professional Dosage Administration

Dacotin 100 Infusion must be used strictly as directed by a healthcare professional. It is intended for intravenous infusion and should not be self-administered. Accurate dosing and timing determined by your doctor ensure safety and effectiveness during cancer treatment. Always consult your physician for the correct dosage plan.


Distribution and Storage Guidelines

This medicine is distributed, supplied, and traded by established vendors across India. To preserve the medicines integrity, store Dacotin 100 Infusion in a cool, dry location away from direct sunlight. Proper storage is crucial for maintaining its therapeutic effectiveness.