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Alkeran 50 Mg Injection

Name: Alkeran 50 Mg Injection
Brand: SIDMEX INOVIA PRIVATE LIMITED
Price: 456.0 INR
Availability: InStock

Price 456.0 INR/ Pack

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MOQ : 496 Packs

Alkeran 50 Mg Injection Specification

Drug Type
Injection

Physical Form
Liquid

Recommended For
Doctor

Dosage Guidelines
As per Instructions

Suitable For
Adults

Storage Instructions
Cool & Dry Place

Alkeran 50 Mg Injection Trade Information

Minimum Order Quantity
496 Packs

Payment Terms
Cash Advance (CA), Cash in Advance (CID), Telegraphic Transfer (T/T)

Supply Ability
6000 Packs Per Week

Delivery Time
4 Days

Sample Available
No

Sample Policy
If order is confirmed we will reimburse the sample cost

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

About Alkeran 50 Mg Injection

1. Technical Specifications

Attribute	Details
Brand Name	Alkeran 50mg Injection
Generic Name	Melphalan
Strength	50 mg per vial (lyophilized powder for reconstitution)
Dosage Form	Injection (for Intravenous use only)
Packaging Size	Single-use vial (with diluent for reconstitution)
Packaging Type	Glass vial with rubber stopper & flip-off seal
Medicine Type	Anticancer Chemotherapy (Alkylating Agent)
Manufacturer	GlaxoSmithKline (original brand); available from other oncology manufacturers as well
Distributed By	Authorized oncology distributors / specialty pharmacies

2. Product Description

Alkeran 50mg Injection contains Melphalan, an alkylating cytotoxic chemotherapy agent derived from nitrogen mustard.

It works by alkylating DNA bases, leading to DNA cross-linking, inhibition of DNA and RNA synthesis, and ultimately cell death.

It is primarily used in high-dose conditioning regimens before hematopoietic stem cell transplantation (HSCT) and in the treatment of multiple myeloma.

3. Product Highlights

Attribute	Details
Therapeutic Category	Antineoplastic (Alkylating Agent)
Application Area	Multiple Myeloma, High-dose conditioning in Hematopoietic Stem Cell Transplantation (HSCT), Ovarian cancer (selected cases)
Mechanism of Action	DNA alkylation interstrand cross-linking inhibition of DNA/RNA synthesis apoptosis of rapidly dividing cancer cells
Administration	Intravenous infusion (reconstituted with diluent and further diluted in 0.9% sodium chloride before use). Must be given under specialist supervision.
Storage Conditions	Store unopened vials refrigerated at 28 C. Use immediately after reconstitution (stability limited). Protect from light.

4. Therapeutic Uses

Multiple Myeloma standard treatment, alone or in combination with prednisone or other agents.
High-Dose Therapy for Stem Cell Transplantation used as conditioning regimen in autologous or allogeneic bone marrow transplant.
Ovarian Cancer in advanced or relapsed cases (less common than oral form).

5. Side Effects

Common:

Nausea, vomiting, diarrhea
Oral ulcers, stomatitis
Loss of appetite
Fatigue, weakness

Serious / Severe:

Bone marrow suppression severe neutropenia, thrombocytopenia, anemia
Risk of serious infections due to immunosuppression
Pulmonary toxicity (fibrosis, pneumonitis rare but life-threatening)
Hepatotoxicity (veno-occlusive disease with high-dose therapy)
Secondary malignancies (long-term use risk: leukemia, MDS)
Hypersensitivity reactions (rare)

6. Precautions

Monitoring: CBC, liver function, renal function must be checked regularly.
Renal Impairment: Dose adjustments required; melphalan is renally excreted.
Hepatic Impairment: Caution advised.
Pregnancy & Breastfeeding: Contraindicated (highly teratogenic, mutagenic, carcinogenic). Reliable contraception required.
Handling: Cytotoxicuse protective equipment during preparation and disposal.
Drug Interactions: Avoid live vaccines; additive toxicity with other bone marrow-suppressive or hepatotoxic drugs.

Effective Cancer Treatment

Alkeran 50 Mg Injection delivers effective results in managing cancers like multiple myeloma and ovarian cancer. Its formulation ensures targeted action against cancer cells, leading to improved patient outcomes under medical supervision.

Usage and Administration

This liquid injection must be administered as per the doctors instructions, typically in a clinical setting due to its potent nature. Dosage and frequency depend on individual patient needs and are decided by the treating physician.

FAQs of Alkeran 50 Mg Injection:

Q: How should Alkeran 50 Mg Injection be stored to maintain its effectiveness?

A: Alkeran 50 Mg Injection should be stored in a cool and dry place, away from direct sunlight and moisture, to preserve its efficacy and safety.

Q: What is the recommended usage process for Alkeran 50 Mg Injection?

A: The injection is administered intravenously or as directed by a healthcare professional. It must only be given under medical supervision according to the prescribed dosage and schedule.

Q: When is Alkeran 50 Mg Injection typically used in cancer treatment?

A: Alkeran 50 Mg Injection is prescribed as a part of chemotherapy regimens, usually when indicated for cancers such as multiple myeloma and ovarian cancer in adults, and only after assessment by a doctor.

Q: Where can I obtain Alkeran 50 Mg Injection in India?

A: Alkeran 50 Mg Injection is distributed throughout India by authorized distributors, exporters, suppliers, traders, and wholesalers. Always ensure you acquire it from reputable medical sources.

Q: What are the potential benefits of using Alkeran 50 Mg Injection?

A: Alkeran 50 Mg Injection can slow or stop the proliferation of cancer cells, contributing significantly to improved treatment outcomes for certain cancers when used as directed by a healthcare professional.

Q: Who is suitable for receiving Alkeran 50 Mg Injection?

A: This medication is recommended for adults diagnosed with specific cancers, under strict medical supervision. Always consult a doctor to confirm suitability and appropriate dosage guidelines.

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