Vingraf 2mg Capsule

Product Description

1. Technical Specifications

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2. Product Description

Vingraf 2 mg Capsule contains Tacrolimus, an immunosuppressant that works by inhibiting calcineurin, thereby suppressing T-lymphocyte activation. This reduces immune responses and prevents the body from rejecting transplanted organs. It is widely used in post-transplant care to maintain graft survival and reduce the risk of organ rejection.

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3. Product Highlights

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4. Therapeutic Uses

• Prevention of organ rejection in kidney, liver, and heart transplant patients

• Sometimes used in rescue therapy for patients not responding to other immunosuppressants

• May be prescribed in certain autoimmune conditions (off-label, under specialist supervision)

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5. Side Effects

Common: Tremors, headache, nausea, diarrhea, high blood pressure, increased blood sugar, insomnia.

Serious:

• Nephrotoxicity (kidney damage)

• Neurotoxicity (seizures, confusion, neuropathy)

• Increased risk of infections due to immune suppression

• Diabetes mellitus post-transplant

• Increased risk of malignancies (e.g., lymphoma, skin cancer)

• Electrolyte imbalances (high potassium, low magnesium)

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6. Precautions

• To be taken strictly under supervision of a transplant specialist.

• Regular monitoring of tacrolimus blood levels, kidney function, liver function, and electrolytes is required.

• Dose adjustments may be needed depending on drug levels and patient condition.

• Avoid grapefruit and grapefruit juice (alters tacrolimus metabolism).

• Contraindicated in patients with hypersensitivity to Tacrolimus.

• Increased risk of drug interactions (CYP3A4 inhibitors/inducers).

• Patients should avoid excessive sunlight exposure (risk of skin cancer).

Key Features and Benefits

Vingraf facilitates successful organ transplant outcomes by minimizing the bodys immune response against transplanted kidney, liver, or heart tissue. Its active ingredient, Tacrolimus, ensures effective immunosuppression, helping adult patients avoid rejection episodes. The capsules oral form offers convenience, while its precise dosage and quality packaging protect its potency and safety.


Proper Administration and Storage

For best results, Vingraf capsules should be taken exactly as prescribed by your physician, usually once or twice daily, ideally at the same time each day. You can take them with or without food, as advised. Protect the capsules from moisture and light, and keep them stored below 25C. Never exceed the recommended dosage without consulting your doctor.


Safety Precautions and Side Effects

Vingraf is suitable for adult transplant recipients only, under medical supervision. Common side effects include tremors, headaches, hypertension, and renal dysfunction; always report any unusual symptoms to your healthcare provider. Use during pregnancy or breastfeeding is not recommended unless specifically instructed by your doctor. Regular medical check-ups are necessary while using Vingraf.