Tigez 50 Mg Injection
Tigez 50 Mg Injection

Tigez 50 Mg Injection

Price 3033.0 INR/ Pack

MOQ : 7 Packs

Tigez 50 Mg Injection Specification

  • Pacakaging (Quantity Per Box)
  • 1 vial per box
  • Origin of Medicine
  • Allopathic
  • Dosage Form
  • Injection
  • Indication
  • Complicated skin and soft tissue infections, complicated intra-abdominal infections
  • Salt Composition
  • Tigecycline 50 mg
  • Drug Type
  • Prescription
  • Ingredients
  • Tigecycline
  • Physical Form
  • Injection
  • Function
  • Antibacterial
  • Recommended For
  • Adults
  • Dosage
  • As directed by physician
  • Dosage Guidelines
  • Intravenous use only
  • Quantity
  • 1 vial
  • Storage Instructions
  • Store below 25C, protected from light
  • Color
  • Yellow to orange powder
  • Route of Administration
  • Intravenous
  • Prescription Required
  • Yes
  • Reconstitution Required
  • Yes, with sterile water for injection
  • Therapeutic Class
  • Antibiotics
  • Packing Type
  • Glass vial with stopper
  • Shelf Life
  • 24 months
 

Tigez 50 Mg Injection Trade Information

  • Minimum Order Quantity
  • 7 Packs
  • Payment Terms
  • Telegraphic Transfer (T/T), Cash in Advance (CID), Cash Advance (CA)
  • Supply Ability
  • 1000 Packs Per Week
  • Delivery Time
  • 6 Days
  • Sample Available
  • Yes
  • Sample Policy
  • If order is confirmed we will reimburse the sample cost
  • Main Export Market(s)
  • Asia, Australia, Central America, South America, Eastern Europe, Western Europe, North America, Africa, Middle East
  • Main Domestic Market
  • All India
 

About Tigez 50 Mg Injection

1. Technical Specifications

Attribute Details
Brand Name Tigez Injection
Generic Name Tigecycline
Strength 50 mg per vial
Dosage Form Lyophilized powder for reconstitution (IV injection/infusion)
Packaging Size Single vial
Packaging Type Glass vial with sterile powder
Medicine Type Allopathic, Antibiotic
Manufacturer Natco Pharma Ltd.
Distributed By Authorized distributors

2. Product Description

Tigez 50 mg Injection contains Tigecycline, a broad-spectrum glycylcycline antibiotic structurally related to tetracyclines. It acts by binding to the 30S ribosomal subunit, thereby inhibiting bacterial protein synthesis and preventing bacterial growth.

It is given intravenously after reconstitution and is reserved for complicated infections due to its broad activity against multi-drug resistant organisms.


3. Product Highlights

Attribute Details
Therapeutic Category Glycylcycline antibiotic
Application Area Severe bacterial infections resistant to standard antibiotics
Mechanism of Action Inhibits bacterial protein synthesis by binding to 30S ribosomal subunit
Administration Intravenous infusion (over 3060 minutes) after reconstitution with sterile solution
Storage Conditions Store below 25C; protect from light; reconstituted solution stable for limited time only

4. Therapeutic Uses

  • Complicated intra-abdominal infections

  • Complicated skin and soft tissue infections

  • Community-acquired pneumonia (when alternatives are unsuitable)

  • Active against many resistant pathogens: MRSA, VRE, ESBL-producing organisms


5. Side Effects

Common:

  • Nausea, vomiting, diarrhea

  • Headache, dizziness

  • Injection site reactions

  • Increased liver enzymes

Serious / Severe:

  • Pancreatitis

  • Severe hepatic impairment

  • Increased risk of mortality in some severe infections (black box warning)

  • Superinfections including Clostridioides difficile-associated diarrhea

  • Hypersensitivity or anaphylaxis (rare)


6. Precautions

  • Liver Function: Dose adjustment required in severe hepatic impairment. Monitor liver enzymes regularly.

  • Pregnancy & Breastfeeding: Contraindicated; potential teratogenic effects and excretion in breast milk.

  • Children: Not recommended in patients <8 years due to tooth discoloration and bone growth issues.

  • Drug Interactions: Use with caution alongside anticoagulants (may increase INR). Avoid with other hepatotoxic agents.

  • Resistance: Not for routine use in mild infections; reserve for resistant cases.

  • Mortality Risk: Studies show higher mortality in serious infectionsshould be used when no alternatives are available.



Therapeutic Application of Tigez 50 Mg Injection

Tigez 50 Mg Injection is utilized in clinical settings to manage severe bacterial infections, particularly those affecting the skin, soft tissue, and abdominal area. Its broad-spectrum antibacterial properties make it effective against various resistant pathogens, underscoring its significance for patients with complicated health conditions seeking targeted therapy.


Proper Use and Preparation

Before administration, Tigez 50 Mg Injection must be reconstituted with sterile water for injection as per the guidelines. This process ensures the correct concentration for intravenous delivery. Only trained healthcare professionals should handle preparation and administration to optimize efficacy and minimize risks associated with improper use.


Safe Storage and Shelf Life

Maintaining the stability of Tigez 50 Mg Injection requires strict storage below 25C and protection from light. Each glass vial is engineered to preserve the medicines integrity for up to 24 months. Following these instructions reduces the risk of degradation, ensuring the medications optimal performance when needed.

FAQs of Tigez 50 Mg Injection:


Q: How should Tigez 50 Mg Injection be prepared prior to use?

A: Tigez 50 Mg Injection must be reconstituted with sterile water for injection according to healthcare guidelines before administration. Only trained medical staff should perform this step to ensure safety.

Q: What conditions does Tigez 50 Mg Injection treat?

A: This medication is recommended for adults suffering from complicated skin and soft tissue infections or complicated intra-abdominal infections, as prescribed by a doctor.

Q: When should Tigez 50 Mg Injection be administered?

A: Tigez 50 Mg Injection should be given only when prescribed by a physician, following their specific dosage schedule for intravenous infusion.

Q: Where should Tigez 50 Mg Injection be stored before use?

A: Store the vial below 25C, protected from light, to maintain its efficacy and shelf life until its expiration date.

Q: What is the correct route of administration for Tigez 50 Mg Injection?

A: This injection is intended for intravenous use only and must not be administered by other routes.

Q: What is the primary benefit of Tigez 50 Mg Injection in treatment regimens?

A: The main benefit of Tigez 50 Mg Injection is its effectiveness against resistant bacterial pathogens causing severe infections, providing targeted antibacterial action for complicated cases.

Q: Who is eligible to receive Tigez 50 Mg Injection?

A: Tigez 50 Mg Injection is intended for adult patients and should only be administered under medical supervision as per a physicians instructions.

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