Everolimus 10mg tablet

Name: Everolimus 10mg tablet
Brand: SIDMEX INOVIA PRIVATE LIMITED
Price: 19882.0 INR
Availability: InStock

Price 19882.0 INR/ Pack

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MOQ : 2 Packs

Everolimus 10mg tablet Specification

Dosage Form
Tablet

Origin
India

Ingredients
100% Yeast

Storage Instructions
Cool & Dr Place

Shelf Life
1 Years

Everolimus 10mg tablet Trade Information

Minimum Order Quantity
2 Packs

Payment Terms
Telegraphic Transfer (T/T), Cash Advance (CA), Cash in Advance (CID)

Supply Ability
150 Packs Per Week

Delivery Time
6 Days

Sample Available
No

Sample Policy
If order is confirmed we will reimburse the sample cost

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

About Everolimus 10mg tablet

1. Technical Specifications

Attribute	Details
Brand Name	Afinitor 10mg Tablet
Generic Name	Everolimus
Strength	10 mg
Dosage Form	Oral Tablet (film-coated)
Packaging Size	Strip of 10 tablets / bottle (as per market availability)
Packaging Type	Blister pack or HDPE bottle with desiccant
Medicine Type	Targeted Anticancer / Immunosuppressant (mTOR inhibitor)
Manufacturer	Novartis Pharmaceuticals
Distributed By	Authorized oncology distributors / specialty pharmacies

2. Product Description

Afinitor 10mg Tablet contains Everolimus, a selective mTOR (mammalian target of rapamycin) inhibitor.
It reduces cell proliferation, angiogenesis, and cancer cell survival by inhibiting the mTOR signaling pathway.

Also acts as an immunosuppressant in transplant medicine and as targeted therapy in certain cancers.

3. Product Highlights

Attribute	Details
Therapeutic Category	Targeted Anticancer Therapy / Immunosuppressant
Application Area	Breast cancer (HR+, HER2-), Renal cell carcinoma, Pancreatic NET, Subependymal giant cell astrocytoma (SEGA), Tuberous sclerosisassociated renal angiomyolipoma
Mechanism of Action	Inhibits mTOR kinase blocks downstream signaling of PI3K/AKT pathway suppresses tumor cell growth, angiogenesis, and survival
Administration	Oral, once daily, same time each day, swallowed whole with water (with or without food but consistently)
Storage Conditions	Store below 30 C, in original packaging, protect from moisture & light

4. Therapeutic Uses

Advanced Breast Cancer (HR+, HER2-, postmenopausal women): In combination with exemestane
Advanced Renal Cell Carcinoma: After failure of VEGF-targeted therapy
Neuroendocrine Tumors (pancreatic NET, GI, lung): Unresectable, locally advanced or metastatic disease
Subependymal Giant Cell Astrocytoma (SEGA): Associated with tuberous sclerosis (when surgery is not feasible)
Renal Angiomyolipoma: In patients with tuberous sclerosis

5. Side Effects

Common:

Stomatitis (mouth ulcers)
Rash, pruritus, acne
Fatigue, weakness
Decreased appetite, weight loss
Diarrhea, nausea
Infections (respiratory, urinary tract)
Cough, dyspnea

Serious / Severe:

Non-infectious pneumonitis (serious lung toxicity)
Severe infections due to immunosuppression
Stomatitis with ulceration
Hepatotoxicity (elevated liver enzymes)
Renal failure (rare but serious)
Hyperglycemia, hyperlipidemia
Myelosuppression (low WBC, platelets, anemia)

6. Precautions

Blood Monitoring: CBC, liver & kidney function, fasting glucose & lipid profile regularly.
Infection Risk: Avoid exposure to sick contacts; report fever, cough, or breathing difficulty immediately.
Oral Care: Maintain good oral hygiene; early treatment of mouth ulcers recommended.
Pregnancy & Breastfeeding: Contraindicated; Everolimus is teratogenic.
Drug Interactions:
- Metabolized by CYP3A4 avoid strong inhibitors (ketoconazole, clarithromycin) & inducers (rifampicin, phenytoin).
- Avoid live vaccines.
Pulmonary Monitoring: Discontinue if severe non-infectious pneumonitis develops.

Storage and Handling

For optimal effectiveness and longevity, Everolimus 10mg tablets should be stored in a cool, dry place, away from direct sunlight and moisture. Proper storage maintains the tablets potency and ensures patient safety throughout its shelf life.

Quality and Sourcing

Sourced and manufactured in India, Everolimus 10mg tablets use 100% yeast-based ingredients. Distributed through experienced suppliers, they adhere to strict quality assurance standards, making them suitable for a wide range of buyers, including exporters and wholesalers.

FAQs of Everolimus 10mg tablet:

Q: How should Everolimus 10mg tablets be used for maximum benefit?

A: Always take Everolimus 10mg tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole, do not crush or chew, and follow your physicians dosing schedule for best therapeutic outcomes.

Q: What is the recommended storage method for Everolimus 10mg tablets?

A: To preserve potency and quality, store Everolimus 10mg tablets in a cool, dry place, away from humidity and direct sunlight. Avoid storing them in bathrooms or near heat sources.

Q: When does the effectiveness of Everolimus 10mg tablets expire?

A: Everolimus 10mg tablets have a shelf life of 1 year from the manufacturing date. Always check the expiration date on the packaging before use and avoid using expired medication.

Q: Where are Everolimus 10mg tablets manufactured and supplied from?

A: These tablets are manufactured in India, a country recognized for robust pharmaceutical production, and are distributed by Indian wholesalers, exporters, suppliers, and traders to domestic and international markets.

Q: What is the process behind sourcing the ingredients for Everolimus 10mg tablets?

A: Everolimus 10mg tablets are formulated using 100% yeast-derived ingredients, ensuring natural sourcing and adherence to stringent quality standards during production in India.

Q: What are the primary benefits of using Everolimus 10mg tablets?

A: Everolimus 10mg tablets offer targeted therapeutic benefits as recommended by medical professionals. Their consistent formulation and quality sourcing provide reliable support for prescribed treatments.

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