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Canmab 440mg Injection

Name: Canmab 440mg Injection
Brand: SIDMEX INOVIA PRIVATE LIMITED
Price: 51763.0 INR
Availability: InStock

Price 51763.0 INR/ Pack

Get a Price/Quote

MOQ : 10 Packs, Pack

Canmab 440mg Injection Specification

Salt Composition
Trastuzumab Lyophilized Powder For Concentrate For Solution For Infusion eq. to Trastuzumab 440mg, Sterile Water for Injection 20ml

Indication
Treatment of HER2-positive breast cancer and gastric cancer

Dosage Form
Injection

Origin
India

Ingredients
Trastuzumab

Application
Hospital, Oncology Use

Physical Color/Texture
White lyophilized powder with sterile water for injection

Fermentation Smell
Odorless

Storage Instructions
Cool & Dr Place

Shelf Life
1 Years

Prescription/Non-prescription
Prescription only medicine

Reconstitution
Requires reconstitution before use

Brand Name
Canmab

Route of Administration
Intravenous infusion

ATC Code
L01XC03

Container Type
Glass vial

Packaging Size
Vial containing 440mg powder with 20ml sterile water

Marketed By
Mylan

Therapeutic Category
Antineoplastic agents

Storage Conditions After Reconstitution
Use within prescribed time or as per manufacturer guidelines

Canmab 440mg Injection Trade Information

Minimum Order Quantity
10 Packs, Pack

Payment Terms
Cash Advance (CA), Cash in Advance (CID), Telegraphic Transfer (T/T)

Supply Ability
100 Packs, Pack Per Week

Delivery Time
1 Days

Sample Available
No

Sample Policy
If order is confirmed we will reimburse the sample cost

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

About Canmab 440mg Injection

1. Technical Specifications

Brand	Biocon
Usage	Commercial,Personal,Hospital,Clinical
Dose	440 mg
Packaging Type	Box
Usage	Commercial, Clinical, Hospital, Personal

2. Product Description

Canmab 440 mg Injection contains Trastuzumab, a recombinant humanized monoclonal antibody that specifically binds to the HER2/neu receptor (human epidermal growth factor receptor 2). It is used in the treatment of HER2-positive breast and gastric cancers.
Canmab is the biosimilar of Herceptin (Roche) and is widely used across oncology settings for both early-stage and metastatic HER2-positive breast cancer.

3. Product Highlights

Brand Name: Canmab
Generic Name: Trastuzumab for Injection
Dosage Form: Lyophilized powder for intravenous infusion
Dosage Form: Lyophilized powder for intravenous infusion
Therapeutic Category: Monoclonal Antibody / Antineoplastic
Route of Administration: Intravenous infusion
Storage:

Store at 28C
Do not freeze
Protect from light
Use reconstituted solution within 24 hours if refrigerated

4. Therapeutic Uses

HER2-positive metastatic breast cancer (alone or with paclitaxel/docetaxel)
Adjuvant treatment of HER2-positive early breast cancer
HER2-positive gastric and gastroesophageal junction adenocarcinoma (in combination with chemotherapy)

Used under oncologist supervision after confirming HER2 overexpression via IHC or FISH testing.

5. Safety Profile & Side Effects

Common adverse effects:

Fever, chills
Nausea, vomiting
Infusion-related reactions
Headache, fatigue, rash
Diarrhea

Serious adverse effects:

Cardiotoxicity (congestive heart failure, especially with anthracyclines)
Pulmonary toxicity (rare)
Hypersensitivity or anaphylaxis
Myelosuppression (less common)

6. Precautions:

Perform baseline and periodic LVEF (echocardiogram)
Monitor for infusion-related reactions (especially first dose)
Do not mix with dextrose-containing solutions
Pregnancy Category D contraindicated in pregnancy
Not interchangeable with SC trastuzumab or trastuzumab-DM1 formulations

How Canmab 440mg Injection Works

Canmab contains Trastuzumab, a monoclonal antibody specifically targeting the HER2 receptor, which is often overexpressed in some breast and gastric cancers. By binding to this receptor, Canmab helps inhibit cancer cell growth and can enhance the effect of other anticancer treatments. Its targeted action makes it a valuable component in HER2-positive cancer therapy.

Proper Usage and Administration

Canmab 440mg Injection must be reconstituted with the supplied sterile water and administered intravenously by healthcare professionals. The vial should be prepared in a controlled hospital environment and infused slowly, ensuring patient safety and optimal drug effectiveness. Dosage and infusion frequency will be determined by an oncologist, based on individual patient needs and treatment response.

Safe Storage and Handling Guidelines

Store Canmab in a cool, dry place before reconstitution. After reconstitution, use the solution within the time frame prescribed by the manufacturer or healthcare provider. Proper storage maintains the drugs potency and integrity, ensuring reliable therapeutic performance. Discard any unused reconstituted solution as per hospital protocols to avoid potential risk or contamination.

FAQs of Canmab 440mg Injection:

Q: How is Canmab 440mg Injection prepared and administered?

A: Canmab 440mg Injection requires reconstitution by dissolving the lyophilized powder with the provided sterile water. The prepared solution is administered intravenously by a healthcare professional, typically in a hospital setting.

Q: What conditions is Canmab 440mg Injection used to treat?

A: Canmab is primarily indicated for the treatment of HER2-positive breast cancer and HER2-positive gastric cancer, as determined by specific diagnostic testing.

Q: When should Canmab 440mg Injection be used after reconstitution?

A: After reconstitution, Canmab should be used within the time period specified in the manufacturers instructions or as directed by the prescribing physician. This ensures the medications effectiveness and safety.

Q: Where should Canmab 440mg Injection be stored?

A: Unreconstituted Canmab should be stored in a cool, dry place. Once the powder is reconstituted into solution, it should be used promptly and stored according to the manufacturers recommendations or discarded appropriately.

Q: What are the benefits of using Canmab for cancer patients?

A: Canmab targets the HER2 receptor, directly inhibiting cancer cell growth and improving patient outcomes when used in conjunction with other cancer therapies, making it a key agent in HER2-positive cancer management.

Q: What is the process for obtaining Canmab 440mg Injection?

A: This medication is available by prescription only and should be dispensed through authorized hospital pharmacies, under the supervision of a qualified physician. It is primarily distributed to oncology centers and hospitals.

Q: Is Canmab 440mg Injection suitable for all cancer patients?

A: No, Canmab is intended specifically for patients diagnosed with HER2-positive tumors. Its use is determined by testing for HER2 protein overexpression and should only be initiated by an oncologist familiar with this therapy.

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