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Canmab 440mg Injection

Canmab 440mg Injection

51763.0 INR/Pack
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Product Details:

  • Indication Treatment of HER2-positive breast cancer and gastric cancer
  • Salt Composition Trastuzumab Lyophilized Powder For Concentrate For Solution For Infusion eq. to Trastuzumab 440mg, Sterile Water for Injection 20ml
  • Origin India
  • Dosage Form Injection
  • Feature Monoclonal antibody, Anticancer agent
  • Ingredients Trastuzumab
  • Application Hospital, Oncology Use
  • Click to view more
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Canmab 440mg Injection Price And Quantity

  • 51763.0 INR/Pack
  • 4 Pack

Canmab 440mg Injection Product Specifications

  • Monoclonal antibody, Anticancer agent
  • Injection
  • India
  • Trastuzumab Lyophilized Powder For Concentrate For Solution For Infusion eq. to Trastuzumab 440mg, Sterile Water for Injection 20ml
  • Odorless
  • Treatment of HER2-positive breast cancer and gastric cancer
  • Cool & Dr Place
  • White lyophilized powder with sterile water for injection
  • Trastuzumab
  • 1 Years
  • Hospital, Oncology Use

Canmab 440mg Injection Trade Information

  • Cash Advance (CA), Cash in Advance (CID), Telegraphic Transfer (T/T)
  • 100 Pack Per Week
  • 1 Days
  • No
  • If order is confirmed we will reimburse the sample cost
  • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
  • All India

Product Description

1. Technical Specifications

Brand

Biocon

Usage

Commercial,Personal,Hospital,Clinical

Dose

440 mg

Packaging Type

Box
Usage Commercial, Clinical, Hospital, Personal


2. Product Description

Canmab 440 mg Injection contains Trastuzumab, a recombinant humanized monoclonal antibody that specifically binds to the HER2/neu receptor (human epidermal growth factor receptor 2). It is used in the treatment of HER2-positive breast and gastric cancers.
Canmab is the biosimilar of Herceptin (Roche) and is widely used across oncology settings for both early-stage and metastatic HER2-positive breast cancer.

3. Product Highlights

  • Brand Name: Canmab

  • Generic Name: Trastuzumab for Injection

  • Dosage Form: Lyophilized powder for intravenous infusion

  • Dosage Form: Lyophilized powder for intravenous infusion

  • Therapeutic Category: Monoclonal Antibody / Antineoplastic

  • Route of Administration: Intravenous infusion

  • Storage:

    • Store at 28C

    • Do not freeze

    • Protect from light

    • Use reconstituted solution within 24 hours if refrigerated


4. Therapeutic Uses

  • HER2-positive metastatic breast cancer (alone or with paclitaxel/docetaxel)

  • Adjuvant treatment of HER2-positive early breast cancer

  • HER2-positive gastric and gastroesophageal junction adenocarcinoma (in combination with chemotherapy)


Used under oncologist supervision after confirming HER2 overexpression via IHC or FISH testing.


5. Safety Profile & Side Effects

Common adverse effects:

  • Fever, chills

  • Nausea, vomiting

  • Infusion-related reactions

  • Headache, fatigue, rash

  • Diarrhea

Serious adverse effects:

  • Cardiotoxicity (congestive heart failure, especially with anthracyclines)

  • Pulmonary toxicity (rare)

  • Hypersensitivity or anaphylaxis

  • Myelosuppression (less common)


6. Precautions:

  • Perform baseline and periodic LVEF (echocardiogram)

  • Monitor for infusion-related reactions (especially first dose)

  • Do not mix with dextrose-containing solutions

  • Pregnancy Category D contraindicated in pregnancy

  • Not interchangeable with SC trastuzumab or trastuzumab-DM1 formulations



How Canmab 440mg Injection Works

Canmab contains Trastuzumab, a monoclonal antibody specifically targeting the HER2 receptor, which is often overexpressed in some breast and gastric cancers. By binding to this receptor, Canmab helps inhibit cancer cell growth and can enhance the effect of other anticancer treatments. Its targeted action makes it a valuable component in HER2-positive cancer therapy.


Proper Usage and Administration

Canmab 440mg Injection must be reconstituted with the supplied sterile water and administered intravenously by healthcare professionals. The vial should be prepared in a controlled hospital environment and infused slowly, ensuring patient safety and optimal drug effectiveness. Dosage and infusion frequency will be determined by an oncologist, based on individual patient needs and treatment response.


Safe Storage and Handling Guidelines

Store Canmab in a cool, dry place before reconstitution. After reconstitution, use the solution within the time frame prescribed by the manufacturer or healthcare provider. Proper storage maintains the drugs potency and integrity, ensuring reliable therapeutic performance. Discard any unused reconstituted solution as per hospital protocols to avoid potential risk or contamination.

FAQs of Canmab 440mg Injection:


Q: How is Canmab 440mg Injection prepared and administered?

A: Canmab 440mg Injection requires reconstitution by dissolving the lyophilized powder with the provided sterile water. The prepared solution is administered intravenously by a healthcare professional, typically in a hospital setting.

Q: What conditions is Canmab 440mg Injection used to treat?

A: Canmab is primarily indicated for the treatment of HER2-positive breast cancer and HER2-positive gastric cancer, as determined by specific diagnostic testing.

Q: When should Canmab 440mg Injection be used after reconstitution?

A: After reconstitution, Canmab should be used within the time period specified in the manufacturers instructions or as directed by the prescribing physician. This ensures the medications effectiveness and safety.

Q: Where should Canmab 440mg Injection be stored?

A: Unreconstituted Canmab should be stored in a cool, dry place. Once the powder is reconstituted into solution, it should be used promptly and stored according to the manufacturers recommendations or discarded appropriately.

Q: What are the benefits of using Canmab for cancer patients?

A: Canmab targets the HER2 receptor, directly inhibiting cancer cell growth and improving patient outcomes when used in conjunction with other cancer therapies, making it a key agent in HER2-positive cancer management.

Q: What is the process for obtaining Canmab 440mg Injection?

A: This medication is available by prescription only and should be dispensed through authorized hospital pharmacies, under the supervision of a qualified physician. It is primarily distributed to oncology centers and hospitals.

Q: Is Canmab 440mg Injection suitable for all cancer patients?

A: No, Canmab is intended specifically for patients diagnosed with HER2-positive tumors. Its use is determined by testing for HER2 protein overexpression and should only be initiated by an oncologist familiar with this therapy.

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  • D-620, Swati Clover, Shilaj Cross Road, S. P. Ring Road, Shilaj,Ahmedabad - 380059, Gujarat, India
  • Phone : 08071930881
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  • Mobile : 08071930881
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