About Docetaxel 120mg injection

1. Technical Specifications

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2. Product Description

Docel 120mg Injection contains Docetaxel, a cytotoxic anticancer medicine of the Taxane class.
It inhibits cell division by stabilizing microtubules and preventing their depolymerization, leading to cell cycle arrest and apoptosis (cancer cell death).

It is widely used as a first-line or subsequent therapy in various solid tumors, either as monotherapy or in combination with other chemotherapy agents.

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3. Product Highlights

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4. Therapeutic Uses

• Breast Cancer: Adjuvant treatment, metastatic setting, HER2+ (with trastuzumab).

• Non-Small Cell Lung Cancer (NSCLC): Alone or in combination with platinum compounds.

• Prostate Cancer: In combination with prednisone for metastatic castration-resistant prostate cancer.

• Gastric Cancer: Advanced gastric adenocarcinoma with cisplatin + fluorouracil.

• Head & Neck Cancers: In combination regimens for locally advanced or metastatic disease.

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5. Side Effects

Common:

• Nausea, vomiting, diarrhea

• Hair loss (alopecia)

• Fatigue, weakness

• Mucositis (mouth sores)

• Fluid retention (edema)

Serious / Severe:

• Bone marrow suppression: neutropenia, anemia, thrombocytopenia

• Severe hypersensitivity reactions (requires steroid + antihistamine premedication)

• Peripheral neuropathy: numbness, tingling, weakness in limbs

• Hepatic toxicity (especially in patients with liver impairment)

• Cardiovascular events: arrhythmia, hypotension

• Infections: due to low immunity

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6. Precautions

• Premedication: Dexamethasone required to reduce fluid retention & hypersensitivity.

• CBC Monitoring: Perform before each cycle; withhold/dose reduce in severe neutropenia.

• Liver Function: Contraindicated in severe hepatic impairment; adjust dose in mild/moderate cases.

• Pregnancy & Breastfeeding: Contraindicated; teratogenic.

• Drug Interactions:

  • Avoid strong CYP3A4 inhibitors/inducers (ketoconazole, clarithromycin, rifampicin).

  • Increased toxicity if given with other hepatotoxic or myelosuppressive drugs.

• Neuropathy Monitoring: Patients should report numbness, tingling, or weakness promptly.

Safe and Effective Cancer Therapy

Docetaxel 120mg injection delivers targeted chemotherapy for adult patients battling cancer. Its concentrated formula is designed for intravenous use and is administered exclusively by trained medical experts, ensuring precise dosage and reduced risk of complications. As a trusted solution distributed by leading pharmaceutical providers, its storage requirements and handling guidelines preserve its integrity until it reaches healthcare institutions.


Proper Storage for Maximum Potency

To maintain the effectiveness of Docetaxel 120mg injection, it is essential to store the product in a cool and dry environment. This precaution prevents degradation and preserves the quality of the medication. The product comes in liquid form and is shipped nation-wide to meet the needs of hospitals, clinics, and pharmacies, ensuring accessible care for patients.