Product Description

1. Technical Specifications

---

2. Product Description

Cytalon 500 Injection contains Cytarabine, a pyrimidine antimetabolite chemotherapy drug.
It inhibits DNA synthesis by incorporating into DNA and blocking DNA polymerase, leading to disruption of cell replication and death of rapidly dividing cancer cells.

It is a key part of treatment protocols for acute leukemias and certain lymphomas.

---

3. Product Highlights

---

4. Therapeutic Uses

• Acute Myeloid Leukemia (AML): Standard drug in induction (e.g., 7+3 regimen with anthracyclines) and consolidation therapy.

• Acute Lymphoblastic Leukemia (ALL): Used in selected regimens and CNS prophylaxis.

• Non-Hodgkin Lymphoma (NHL): Part of salvage chemotherapy protocols.

• Chronic Myeloid Leukemia (CML): Useful in blast crisis.

• CNS Leukemia: Administered intrathecally as prophylaxis/treatment (preservative-free preparation required).

---

5. Side Effects

Common:

• Nausea, vomiting, diarrhea

• Stomatitis / mucositis

• Fever, malaise

• Rash or injection site reactions

Serious / Severe:

• Myelosuppression: neutropenia, thrombocytopenia, anemia

• Neurotoxicity: cerebellar dysfunction (ataxia, speech difficulty, confusion), especially at high doses

• Hepatic toxicity: elevated liver enzymes, rare hepatic failure

• Pulmonary toxicity: pneumonitis, ARDS (at high dose)

• Ocular toxicity: conjunctivitis, keratitis (recommend corticosteroid eye drops in high-dose therapy)

• Severe infections due to immunosuppression

• Tumor lysis syndrome in patients with high leukemic burden

---

6. Precautions

• Bone marrow monitoring: CBC required frequently; withhold/adjust dose if counts are very low.

• Neurological monitoring: Especially with high-dose regimens (watch for ataxia, tremors).

• Liver & Kidney function: Dose adjustments required in impairment.

• Pregnancy & Breastfeeding: Contraindicated; cytarabine is teratogenic.

• Eye protection: Use prophylactic corticosteroid eye drops with high-dose therapy.

• Drug Interactions: May enhance toxicity with other cytotoxic agents.

• Intrathecal use: Must be preservative-free; administer only in specialized centers.

Key Features of Cytarabine 500mg Injection

Cytarabine 500mg injection is a reliable solution designed for the treatment of hematological malignancies in adults. Its quality-assured liquid formulation is ideal for doctors to administer in clinical environments. Sourced from reputable distributors and wholesalers in India, this injection meets stringent standards for export and supply, ensuring authenticity and safety.


Safe Handling and Storage

To ensure the efficacy and safety of the Cytarabine 500mg injection, it is crucial to store the medication in a cool and dry place. This condition preserves its chemical stability and prevents degradation. Always consult the label and follow storage guidelines as provided by the manufacturer or healthcare provider.