Apretero 125/80 Kit

Product Description

1. Technical Specifications

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2. Product Description

Apretero 125/80 Kit is a combination antihypertensive therapy containing:

• Perindopril an ACE (angiotensin-converting enzyme) inhibitor that lowers blood pressure by relaxing blood vessels and reducing angiotensin II levels.

• Amlodipine a calcium channel blocker that relaxes vascular smooth muscle, decreasing peripheral resistance and blood pressure.

This combination is designed for patients with hypertension not adequately controlled by monotherapy, offering complementary mechanisms to improve blood pressure control.

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3. Product Highlights

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4. Therapeutic Uses

• Hypertension: First-line or add-on therapy to achieve target blood pressure

• Cardiovascular Risk Reduction: In high-risk patients (may reduce risk of stroke, myocardial infarction, heart failure)

• Combination Therapy: Used when monotherapy with ACE inhibitor or calcium channel blocker is insufficient

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5. Side Effects

Common:

• Dizziness, headache

• Fatigue

• Peripheral edema (ankle swelling)

• Cough (from ACE inhibitor component)

• Flushing

Serious / Severe:

• Hypotension (especially after first dose or in volume-depleted patients)

• Angioedema (rare but potentially life-threatening)

• Hyperkalemia (elevated potassium levels)

• Liver or kidney function abnormalities

• Severe allergic reactions (rare)

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6. Precautions

• Renal Impairment: Monitor kidney function and electrolytes regularly.

• Pregnancy & Lactation: Contraindicated; may cause fetal harm.

• Angioedema History: Avoid ACE inhibitor component if prior angioedema.

• Concomitant Medications: Avoid NSAIDs (can reduce antihypertensive effect and impair kidney function), potassium supplements, or potassium-sparing diuretics.

• Administration Advice: Swallow tablets whole; do not crush. Monitor blood pressure regularly.

Comprehensive Adult Care

Apretero 125/80 Kit is developed with adult patients in mind, focusing on effective and safe treatment. The capsules provide a convenient dosage form as per medical guidance, ensuring that patients receive optimal therapeutic benefits. This medication offers reliable support for adult health needs, as suggested by healthcare professionals.


Stringent Storage Guidelines

To ensure maximum potency and longevity, store Apretero 125/80 Kit capsules in a cool and dry place. Proper storage conditions prevent any deterioration due to humidity or high temperatures, protecting the active ingredients. Following these guidelines enhances the safety and efficacy of the medicine over time.