Aluvia 200mg/50mg

Product Description

1. Technical Specifications

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2. Product Description

Aluvia 200/50 Tablet is a fixed-dose combination antiretroviral drug containing Lopinavir and Ritonavir, used in the management of HIV-1 infection. Ritonavir acts as a pharmacokinetic enhancer by inhibiting the metabolism of Lopinavir, thereby increasing its concentration and effectiveness. It is usually prescribed in combination with other antiretroviral drugs to form Highly Active Antiretroviral Therapy (HAART).

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3. Product Highlights

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4. Therapeutic Uses

• HIV-1 Infection:

  • Used as part of combination antiretroviral therapy (cART/HAART)

  • Helps suppress HIV viral load

  • Improves CD4 cell counts and immune function

  • Delays progression to AIDS

• Post-exposure prophylaxis (PEP) in some protocols (when other options are unavailable)

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5. Side Effects

Common:

• Diarrhea, nausea, abdominal pain

• Headache, dizziness, fatigue

• Rash, itching

• Elevated cholesterol and triglyceride levels

Serious (rare):

• Pancreatitis (abdominal pain, vomiting)

• Liver toxicity (yellowing of skin/eyes, dark urine)

• Cardiac effects (QT prolongation, PR interval changes)

• Severe skin reactions (StevensJohnson syndrome, rare)

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6. Precautions

• Always use in combination with other antiretroviralsnever alone

• Monitor liver function, lipid levels, and glucose during therapy

• Dose adjustment may be needed in hepatic impairment

• May interact with many drugs (e.g., antiarrhythmics, anticonvulsants, rifampicin, certain statins, sedatives)inform doctor about all medicines

• Avoid grapefruit juice (affects drug metabolism)

• Safe use in pregnancy: often preferred in HIV-positive pregnant women (per WHO guidelines)

• Not recommended for patients with severe hepatic dysfunction

• Strict adherence is necessary to prevent drug resistance

Powerful Antiretroviral Therapy

Aluvia 200mg/50mg Tablets offer effective management of HIV infection, combining two medicineslopinavir and ritonavirto inhibit the replication of the virus. This dual-action approach helps in reducing the viral load and improving immune function in adult patients when administered according to doctors recommendations.


Proper Storage for Maximum Effectiveness

To preserve the quality and potency of Aluvia Tablets, it is important to store them in a cool and dry place. Exposure to excessive heat or moisture could compromise the medicines effectiveness, so always ensure safe storage conditions as specified on the packaging.